Can Using Only A Single Transdermal Fentanyl Patch Be Fatal?

Fatal overdose after ingestion of a transdermal fentanyl patch in two non-human primates.

UNLABELLED CASE HISTORY AND PRESENTATION: Two non-human primates (Macaca fascicularis), weight 3.5 kg, enrolled in an experimental protocol received a 25 μg hour(-1) transdermal fentanyl patch for postoperative analgesia. The following day both animals were clinically normal, but after a new induction of anaesthesia with ketamine, they developed severe and prolonged respiratory distress, profou...

Fatal intravenous misuse of transdermal fentanyl.

The introduction of a transdermal delivery system for fentanyl means that it is now more readily available. We present the first documented fatality after intravenous injection of the contents of a transdermal fentanyl patch. Prescribers need to be aware of the potential for misuse of fentanyl patches.

Quantum proofs can be verified using only single qubit measurements

QMA (Quantum Merlin Arthur) is the class of problems which, though potentially hard to solve, have a quantum solution which can be verified efficiently using a quantum computer. It thus forms a natural quantum version of the classical complexity class NP (and its probabilistic variant MA, Merlin-Arthur games), where the verifier has only classical computational resources. In this paper, we stud...

Transdermal fentanyl patch in post-operative patients: Is it justified?

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Suspected respiratory depression associated with use of transdermal fentanyl patch.